Document 2613
 DOCN  M94A2613
 TI    HIV & hepatitis B (HBV) in women--a retrospective chart review.
 DT    9412
 AU    Keohane DJ; Flanigan T; Feller E; Carpenter C; Miriam Hospital--Brown
       Univ., Providence, RI 02906.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):264 (abstract no. PB0486). Unique
       Identifier : AIDSLINE ICA10/94369962
 AB    OBJECTIVE: To examine the prevalence of HBV in HIV seropositive women.
       METHODS: A retrospective chart review was undertaken at 3 hospital
       centers. 218 HIV positive women with complete panels of HBV serologies
       were included. RESULTS: In the entire cohort, the incidence of past or
       present HBV infection was 143 of 218 (66%). When evaluated by risk
       factor, 113 of 130 (87%) women with intravenous drug use (IDU) and 28 of
       82 (34%) with unprotected heterosexual exposure were coinfected. When
       evaluated by serologic pattern of HBV positivity, the following was
       found. 10 (7%) women had HBsAb alone, 53 (38%) had HBcAb alone, 75 (53%)
       had HBsAb/HBcAb positivity and 3 (2%) had persistence of HBsAg. All
       three women with persistence of HBsAg had IDU as their risk factor.
       DISCUSSION & CONCLUSION: Our data suggest that IDU represents the
       highest risk behavior for coinfection of HIV and HBV in women. Our
       results also show a low rate of persistent HBsAg and a high rate of
       isolated HBcAb positivity in women who are coinfected as compared to
       prior studies in men.
 DE    Cohort Studies  Cross-Sectional Studies  Female  Hepatitis
       B/*COMPLICATIONS/DIAGNOSIS/EPIDEMIOLOGY  Hepatitis B Antibodies/BLOOD
       Human  HIV Infections/*COMPLICATIONS/DIAGNOSIS/EPIDEMIOLOGY  Incidence
       Retrospective Studies  Rhode Island/EPIDEMIOLOGY  Risk Factors  MEETING
       ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).