Document 2615
 DOCN  M94A2615
 TI    AIDS and syphilis--an analysis of 129 HIV+ patients.
 DT    9412
 AU    Pavan MH; Fornazieri ME; Abreu WB; Lima JN; Monteiro DT; Aoki FH; Inf.
       Dis. Division-FMSc-St. Univ. of Campinas, SP, Brazil.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):264 (abstract no. PB0485). Unique
       Identifier : AIDSLINE ICA10/94369960
 AB    OBJECTIVES: The main objective of this study is analyze the frequency of
       syphilis in 129 HIV1 infected patients, the behaviour of non-treponemic
       and treponemic testings and the spinal fluid analysis. METHODS: 129 HIV1
       infected patients were studied retrospectively, followed at the
       Ambulatory of HIV positive patients, from the Infectious Diseases
       Division of this University. The main age were 29.61 (17-54) years old,
       being 89(69%) from male sex and 40(31%) from female sex. The CDC
       classification for these patients were: Group II-100(77.5%); Group
       III-16(12.4%); Group IV-13(10.1%). The risk behaviour were:
       IVDU-49(39.5%) Real contact with HIV+-21(16.3%); Homossexual-16(12.4%);
       Promiscuous heterossexual-08(6.2%); Suspected contact with
       HIV+-08(6.2%); Bissexual-07(5.4%); Bissex/IVDU-07(5.4%); Common
       transfusion-04(3.1%); No risk group-04(3.1%); Promisc.
       heterossex/IVDU-04(3.1%); Bissex/Common transf.-01(0.8%);
       Heterossex/Common transf-01(0.8%). From 15 patients VDRL+, 7(46.7%) were
       bissexuals, 5(33.3%) IVDU, 1(4.7%) infected by real contact, 1(4.7%) was
       promiscuous heterossexual and 1(4.7%) was bissexual. Thus, 10 patients
       were infected by sexual transmission and 5 by blood contamination.
       RESULTS: From these 15 patients, 5 were not be investigated with spinal
       fluid punction, for any reason. The other 10 patients were punctioned
       with analysis of these fluids. From these 10 patients, 02(20%) had an
       increasing on a white cell count and 1 of these 2, reagents for VDRL at
       the spinal fluid. These 2 patients were treated with penicilin cristalin
       and penicilin procain. Two others (20%) were treated with the same
       scheme, one by maintence of headache and another by anexitis. Ten
       patients from 15 were treated with usual dosis of penicilin benzatin and
       1 were not trated, because the TPHA was not be reagent. After treatment
       9 patients had an adequate response with treatment, according the CDC
       parameters. 2 from 14 had treatment failure, being necessary a
       retreatment. 3 of 14 patients have abandoned the Service. DISCUSSION AND
       CONCLUSION: 1--The treatment with penicilin cristalin were satisfied in
       this group of who had oportunity to be evaluated and had not signals or
       simptoms, spinal fluid evaluation altered and compatible alterations
       related to the neurosyphilis 2--10(66%) of the patients were infected by
       and 5(33.3%) presumed by blood contact.
 DE    Acquired Immunodeficiency Syndrome/*DIAGNOSIS/DRUG THERAPY/
       TRANSMISSION  Adolescence  Adult  AIDS-Related Opportunistic
       Infections/*DIAGNOSIS/DRUG THERAPY/  TRANSMISSION  Bisexuality  Blood
       Transfusion  Brazil  Female  Homosexuality  Human  HIV
       Seropositivity/*DIAGNOSIS/DRUG THERAPY/TRANSMISSION  *HIV-1  Male
       Middle Age  Penicillins/ADMINISTRATION & DOSAGE  Risk Factors  Syphilis
       Serodiagnosis  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).