Document 2621
 DOCN  M94A2621
 TI    Is regional anesthesia safe for the HIV+ parturient?
 DT    9412
 AU    Dattel BJ; Williams S; Coltrin D; Rubio T; Eastern Virginia Medical
       School, Norfolk.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):262 (abstract no. PB0478). Unique
       Identifier : AIDSLINE ICA10/94369954
 AB    OBJECTIVE: To ascertain whether regional anesthesia in HIV+ parturients
       is associated with an increase in obstetric/anesthetic complications or
       a difference in rate of perinatal transmission. METHODS: Retrospective
       chart review was performed with respect to: type of labor/delivery
       anesthetic, obstetric and anesthetic complications, CD4 count,
       antiretroviral therapy and perinatal transmission. Data was compared by
       Chi-Square. RESULTS: HIV risk factors, perinatal transmission rates, CD4
       counts and use of antiretroviral agents did not differ significantly for
       HIV+ parturients who received epidural anesthesia. Mode of delivery,
       incidence of postpartum hemorrhage and perinatal transmission did not
       differ. No anesthetic complications occurred. The rate of perinatal
       transmission was lower for children delivered by cesarean section than
       by the vaginal route although not statistically significant. TABULAR
       DATA, SEE ABSTRACT VOLUME. CONCLUSIONS: These data show that regional
       anesthesia for HIV+ parturients is safe, and should not be witheld on
       the basis of HIV status. These data suggest that the perinatal
       transmission rates may be lower for children born by cesarean section,
       however, more data is needed to ascertain whether cesarean section
       should be offered to all seropositive women to reduce perinatal
       transmission of HIV.
 DE    *Anesthesia, Epidural  *Anesthesia, Obstetrical  Cesarean Section
       Extraction, Obstetrical  Female  Human  HIV
       Seropositivity/*PHYSIOPATHOLOGY/TRANSMISSION  Infant, Newborn  Labor
       Complications/ETIOLOGY  Leukocyte Count  Pregnancy  Pregnancy
       Complications, Infectious/*PHYSIOPATHOLOGY  Retrospective Studies  Risk
       Factors  T4 Lymphocytes/IMMUNOLOGY  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).