Document 2628
 DOCN  M94A2628
 TI    Meningococcal meningitis in HIV nonvertically infected children.
 DT    9412
 AU    Strauss I; Iagaru R; Pascu G; Colentina Hospital Bucharest, Romania.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):260 (abstract no. PB0468). Unique
       Identifier : AIDSLINE ICA10/94369947
 AB    OBJECTIVE: To describe 5 cases of systemic meningococcal infection with
       meningitis in HIV infected children. METHODS: Retrospective analysis of
       the case reports of 600 children admitted in Colentina Hospital for
       symptomatic HIV infection and AIDS between 1991-1993. RESULTS: Five out
       of 9 purulent meningitis were meningococcal, confirmed by cerebrospinal
       fluid (CSF) smear, cultures and counterimmunoelectrophoresis. Children
       were nonvertically infected in the first year of life through parenteral
       way. No zidovudine had been given. Clinical findings were: specific rush
       (4 cases), gigantic herpes lesions (3 cases), infectious monoarthritis
       (1 case). After 10 days of Penicillin G therapy CSF became normal.
       CONCLUSIONS: No pneumococcal meningitis was described in 600 HIV
       infected children. Two cases of HIV infection were diagnosed at
       admission for meningococcal meningitis with gigantic herpes lesions.
 DE    Acquired Immunodeficiency Syndrome/*DIAGNOSIS/DRUG THERAPY  AIDS-Related
       Opportunistic Infections/*DIAGNOSIS/DRUG THERAPY  Cerebrospinal
       Fluid/MICROBIOLOGY  Child  Human  HIV Infections/*DIAGNOSIS/DRUG THERAPY
       Meningitis, Meningococcal/*DIAGNOSIS/DRUG THERAPY  Penicillin
       G/ADMINISTRATION & DOSAGE  MEETING ABSTRACT

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