Document 2657
 DOCN  M94A2657
 TI    HIV IgA immunoblot as a diagnostic tool in pediatrics.
 DT    9412
 AU    Deluchi G; Canizal AM; Zarwanitzer S; Hirsch R; Sosa CE; Benetucci J;
       Laboratorio Retrovirus FUNDAI, Buenos Aires.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):254 (abstract no. PB0447). Unique
       Identifier : AIDSLINE ICA10/94369918
 AB    OBJECTIVES: To assess an HIV-IgA Immunoblot to be used in early
       diagnosis of pediatric AIDS. METHODS: Forty five frozen serum samples
       from children born to seropositive mothers were analized in comparison
       to co-culture as a standard. Children clinical status was:P0 (n = 19);
       P1 (n = 2) and P2 (n = 24). Immunoblot was performed using an In house
       method after IgG precipitation. RESULTS: Patients were divided in two
       groups. A: 3-6 months and B: older than 6 months of age. TABULAR DATA,
       SEE ABSTRACT VOLUME. CONCLUSIONS: The test showed a good correlation
       with co-culture in the population over 6 months of age. This assay is a
       good alternative to be used in diagnosis of HIV infection in pediatrics
       in developing countries.
 DE    Argentina  *AIDS Serodiagnosis  Child  Child, Preschool  *Developing
       Countries  Human  HIV/*IMMUNOLOGY  HIV Antibodies/*BLOOD  HIV
       Seropositivity/*DIAGNOSIS/IMMUNOLOGY/TRANSMISSION  IgA/*BLOOD
       *Immunoblotting  Infant  Infant, Newborn  Predictive Value of Tests
       Risk Factors  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).