Document 2660
 DOCN  M94A2660
 TI    Seroprevalence of HIV infected children with sickle cell anemia.
 DT    9412
 AU    Lukuni ML; Binda P; Mbensa I; Dpt. Pediatrie, Kinshasa Xi Zaire.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):253 (abstract no. PB0441). Unique
       Identifier : AIDSLINE ICA10/94369915
 AB    OBJECTIVE: As in hemophilia, african children suffering of sickle cell
       anemia are exposed to HIV infection because of regular blood
       transfusions. The aim of this study is to determinate the seroprevalence
       and clinico-biological manifestations of this disease. METHODS: 256
       children with sickle cell anemia and aged less than 12 years were
       followed (127 girls and 129 boys). The HIV test was made according to
       the criterias of CDC (1989). Clinical and biological manifestations were
       also determined. No HIV test was made to the parents. RESULTS: In this
       group, only 14 children were HIV positive (5.5%) with severe clinical
       manifestations and critical biological disturbances especially by a
       significative falling of T4 lymphocytes. DISCUSSION AND CONCLUSION:
       About the HIV infection transmission to the studied children, we can
       rise the role of numerous blood transfusions because no certitude of
       materno-foetal transmission is made. Appropriate preventive measures are
       urgent for reducing seroprevalence of this disease.
 DE    Anemia, Sickle Cell/*EPIDEMIOLOGY  AIDS Serodiagnosis  Blood Transfusion
       Child  *Developing Countries  Human  HIV
       Seropositivity/DIAGNOSIS/*EPIDEMIOLOGY/TRANSMISSION  *HIV Seroprevalence
       Zaire/EPIDEMIOLOGY  MEETING ABSTRACT

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