Document 2672
 DOCN  M94A2672
 TI    Rapid screening tests for HIV.
 DT    9412
 AU    Sciandra M; Brusa T; Lingua A; Sinicco A; Inst. of Infect. Dis., Univ.
       of Turin, Italy.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):250 (abstract no. PB0431). Unique
       Identifier : AIDSLINE ICA10/94369903
 AB    OBJECTIVE: to evaluate sensitivity and specificity of SeroCard HIV1
       (SC1) and SeroCard HIV1/2 antibody test (SC1/2) (Trinity Biotech,
       Dublin, Ireland). METHODS: SC1 was used in 90 subjects; 36 were done in
       blind, 26 in HIV1+, 20 in healthy controls and 8 in subjects with
       undetermined ELISA. We used fresh whole blood. SC1/2 was used in 42
       subjects; 14 were done in blind, 15 in HIV1+, 5 in black race HIV2+
       subjects, 8 in healthy controls; 27 were done using sera, 15 using fresh
       whole blood. Contemporarly we performed ELISA test and WB. RESULTS: SC1:
       no false positive or negative result was observed. Among blind tests we
       saw 6 positive results, confirmed in ELISA and WB. All the 8
       undetermined ELISA subjects resulted HIV1-for SC1 and WB.SC1/2: no false
       positive or negative result was observed. Among blind tests we saw 3
       positive results confirmed in ELISA and WB. All the 5 HIV2+ subjects
       resulted positive for SC1/2 and negative for SC1. The total time require
       to perform the tests is about 7 minutes. CONCLUSION: SC1 and SC1/2 are
       useful kits for the rapid screening of subjects at risk for HIV1/2 in
       emergency departments, infectious diseases departments, prisons, etc.
 DE    AIDS Serodiagnosis/*METHODS  Blotting, Western  Comparative Study
       Enzyme-Linked Immunosorbent Assay  Human  HIV Antibodies/*BLOOD  HIV
       Seropositivity/*DIAGNOSIS/IMMUNOLOGY  HIV-1/*IMMUNOLOGY
       HIV-2/*IMMUNOLOGY  Mass Screening  Predictive Value of Tests  *Reagent
       Kits, Diagnostic  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).