Document 2718
 DOCN  M94A2718
 TI    An in vitro qualitative assay for the detection of antibodies to HIV
       type 1/2 contained in human saliva.
 DT    9412
 AU    Chakrabarti T; Mukherjee K; Majumder K; Paul S; Chakrabarty MS; Virology
       Department, School of Tropical Medicine, Calcutta.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):240 (abstract no. PB0391). Unique
       Identifier : AIDSLINE ICA10/94369857
 AB    OBJECTIVE: There are ample evidences that saliva contain secretary--ab
       against host of infections. Therefore saliva has been recommended as a
       non invasive, safe and effective alternative to serum for HIV-ab
       testings. The present study aims for a comparative evaluation of ab
       detection by serum and saliva specimen in laboratory for diagnosis of
       HIV infection in the Indian situation. METHODS: Saliva is collected from
       a number of confirm cases of HIV infected persons by using a rayon ball
       which placed in the mouth, paying particular attention to the area
       between the teeth and gums, until it is completely saturated with saliva
       and collected in a collection device. RESULTS: As the study does not
       belong to routine screening system but it was undertaken only to see its
       credibility and accountability compared to Western Blot system. Some
       seronegative sera were also included in the test as control. DISCUSSION
       AND CONCLUSIONS: Following the study of 42 test sera the workers came to
       the conclusion that the test apart from its simplicity and
       reproducibility was almost free from any false positive or false
       negative reaction. Other informations are expected to be available from
       the study for presentation in the scientific session of the conference.
 DE    AIDS Serodiagnosis/*METHODS  Blotting, Western  Human  HIV
       Antibodies/*ANALYSIS  HIV Seronegativity/IMMUNOLOGY  HIV
       Seropositivity/*DIAGNOSIS/IMMUNOLOGY  HIV-1/*IMMUNOLOGY
       HIV-2/*IMMUNOLOGY  Predictive Value of Tests  Saliva/*IMMUNOLOGY
       MEETING ABSTRACT

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