Document 2767
 DOCN  M94A2767
 TI    Effect of HIV-1 infection on population growth in rural Rakai District,
       Uganda.
 DT    9412
 AU    Sewankambo NK; Wawer MJ; Gray RH; Serwadda D; Li C; Konde-Lule J; Lainjo
       B; Uganda Virus Research Institute, Entebbe.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):23 (abstract no. 067C). Unique
       Identifier : AIDSLINE ICA10/94369808
 AB    OBJECTIVE: To examine the impact of HIV-1 on population growth in rural
       Rakai district, Uganda. METHODS: One year followup (1990-1991) of a
       population-based open cohort. All consenting residents from 1945
       households in 31 randomly selected community clusters responded annually
       to a KAP questionnaire, and underwent serological testing and a limited
       health exam. Births and deaths in the households were recorded during
       annual enumeration. RESULTS: Based on cohort results, HIV prevalence in
       district adults was projected to be 12.6% in 1990. Extrapolated from the
       cohort, the estimated district crude death rate was 28.1 per 1000
       population, compared to an overall crude birth rate of 45.7 per 1000
       population. Only 16.9% of HIV infected women reported having a birth in
       the intersurvey period, compared to 21.3% for HIV uninfected women (RR =
       0.7, CI 0.5-1.0). The IMR among children of HIV infected women was 210
       per 1000 live births, compared to 112 per 1000 live births for children
       of uninfected women. Extrapolated from cohort data, the annual rate of
       natural population increase in the presence of HIV infection remained at
       17.6 per 1000 population in the district. It is estimated that in the
       absence of HIV infection the rate of natural increase would be 25.3 per
       1000 population. CONCLUSION: Despite high HIV seroprevalence and HIV
       related mortality in Rakai, there is continued population growth.
 DE    Acquired Immunodeficiency Syndrome/EPIDEMIOLOGY/*MORTALITY  Birth Rate
       Cohort Studies  Human  *HIV-1  Knowledge, Attitudes, Practice  Mortality
       *Population Growth  Prevalence  Rural Population  Sampling Studies
       Uganda/EPIDEMIOLOGY  MEETING ABSTRACT

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