Document 2820
 DOCN  M94A2820
 TI    Recovery of an advanced AIDS patient from serious end stage with
       treatment.
 DT    9412
 AU    Andoh Y; Andoh Clinic, Osaka, Japan.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):217 (abstract no. PB0299). Unique
       Identifier : AIDSLINE ICA10/94369755
 AB    OBJECTIVE: To treat a patient with seriously advanced AIDS by promoting
       the host defenses. PATIENT: A 27-year-old woman (170 cm height, 50 kg
       weight; could not walk unaided) was diagnosed as having serious AIDS
       (Western blotting, gp160(+), gp110/120(+), gp41(+), p68(+), p51(+),
       p24(+)) with swallow pain, food intolerance etc., and her CD4 value was
       a low as 0.7% (3.3)/ml, and the prognosis was considered very poor.
       TREATMENT METHODS: The following agents were administered: A herbal
       medicine, Juzen-taiho-to (7.5 g/day), which is reported to promote the
       phagocytic activity of macrophage, the cytotoxic T cell activity and the
       production of g-interferon and IL-2; an H2-blocker, famotidine (40
       mg/day), to inactivate suppressor T cells; Diclofenac sodium, Voltaren
       (50 mg/day), to inhibit the production of prostaglandin which is
       reported to activate suppressor T cells. After 20 days, zidovudine (500
       mg/day), and Alfalfa Tabs (Shaklee Co., USA; 30 tablets/day) which
       contains alfalfa powder, dextrin, fructose, Purloin, perfume, and in
       particular, selenium were also administered. RESULTS: On day 3, the
       level of CD4 positive cells was 0.7%/ml. Her swallow pain improved on
       day 6. Abnormalities in the oral cavity disappeared and the rales in the
       chest had decreased on day 8. On day 13, her weight increased to 54 kg,
       and her physical condition was good. On day 18, the level of CD4
       positive cells continued to be 0.7%/ml. On day 20, her general condition
       showed a marked improvement, and from the day Alfalfa Tabs and
       zidovudine were also administered. On day 22, she was in a good general
       condition and her weight was recovered to 57 kg. On day 27, CD4 positive
       cells showed a level of 3.5%/ml. DISCUSSION AND CONCLUSIONS: The
       patient's symptoms remarkably improved and the percentage of CD4
       positive cells increased five-fold by the current treatment within a
       month. Administration of the agents with the health food product might
       be a good treatment for patients with advanced AIDS.
 DE    Acquired Immunodeficiency Syndrome/DRUG THERAPY/*THERAPY  Adult  Alfalfa
       Biological Response Modifiers/*THERAPEUTIC USE  Case Report  Combined
       Modality Therapy  Diclofenac/THERAPEUTIC USE  Drug Therapy, Combination
       Drugs, Chinese Herbal/*THERAPEUTIC USE  Famotidine/THERAPEUTIC USE
       Female  Human  Japan  Selenium/THERAPEUTIC USE  Zidovudine/THERAPEUTIC
       USE  MEETING ABSTRACT

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