Document 2861
 DOCN  M94A2861
 TI    Influence of antiretroviral treatment on the AIDS patients survival--a
       private practice experience.
 DT    9412
 AU    Del Bianco R; Ministerio da Saude, Sao Paulo, Brazil.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):208 (abstract no. PB0263). Unique
       Identifier : AIDSLINE ICA10/94369714
 AB    OBJECTIVE: To evaluate the relationship between epidemiological and
       clinical data with the survival of AIDS patients. METHODS: Retrospective
       study of 40 adult patients with AIDS seen in the private practice since
       1985 until their death. Age of infection, sex, risk behaviour, CD4 cell
       count were evaluated as well as the use or not of antiretroviral
       therapy. RESULTS: The data of infection could not be precisely
       determined. The mean time of progression from diagnosis of HIV infection
       by serology and full blown AIDS were 18 months. All of the patients were
       men, homo or bisexual; 15 of them have not taken antiretroviral
       treatment. The survival (median) of the patients that had not taken
       antiretroviral therapy was 20 months. The ones who had taken treatment
       (n = 25)-ZDV monotherapy on association with ddI, ddC survived for 26.8
       months (median). CONCLUSIONS: In spite of the small number of patients
       this study shows that with the indication of treatment with
       antiretrovirals, according to the orientation given in Brazil in
       patients with ARC and/or CD4 cell count less than 300 cells/mm3, there
       was an increase on the survival in 6.8 months plus improvement in the
       quality of life.
 DE    Acquired Immunodeficiency Syndrome/*DRUG THERAPY/MORTALITY  Adult
       Antiviral Agents/*THERAPEUTIC USE  Brazil/EPIDEMIOLOGY  Human  Leukocyte
       Count  Male  Quality of Life  Survival Rate  Treatment Outcome  T4
       Lymphocytes  MEETING ABSTRACT

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