Document 2932 DOCN M94A2932 TI Stroke in young HIV patients: association with cocaine abuse and meningitis. DT 9412 AU Qureshi AI; Akbar MS; McGaffigan S; Weissman J; Frankel M; Janssen R SO Int Conf AIDS. 1994 Aug 7-12;10(1):191 (abstract no. PB0194). Unique Identifier : AIDSLINE ICA10/94369643 AB OBJECTIVE: To determine the prevalence and etiology of stroke in HIV+ patients. METHODS: We conducted a retrospective review of medical records of all HIV+ patients admitted to a US public hospital, with diagnosis of stroke during 1989-1993. RESULTS: Of 1171 HIV+ admissions, 36 (3%, mean age 38 years) were admitted with stroke. Stroke was related to cocaine abuse in 15 (41.6%) and meningitis in 7 (19.4%) of the cases. When stratified for age, stroke in HIV+ patients < or = 35 years of age was significantly more likely to be associated with cocaine abuse or meningitis as compared to those > 35 years of age (81.2% vs 45%, p = .03). CONCLUSIONS: Stroke in HIV+ patients is related to cocaine abuse or meningitis, particularly in patients under 35 years. DE Adult AIDS-Related Opportunistic Infections/*COMPLICATIONS/EPIDEMIOLOGY Cerebrovascular Disorders/EPIDEMIOLOGY/*ETIOLOGY *Cocaine Cross-Sectional Studies Female Georgia/EPIDEMIOLOGY Human HIV Seropositivity/*COMPLICATIONS/EPIDEMIOLOGY Incidence Male Meningitis/*COMPLICATIONS/EPIDEMIOLOGY Risk Factors Substance Dependence/*COMPLICATIONS/EPIDEMIOLOGY MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).