Document 2969
 DOCN  M94A2969
 TI    Stomatitis aphthous in patients HIV+, treatment.
 DT    9412
 AU    Lopez J; Rosello X; Jane E; University of Barcelona, Spain.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):183 (abstract no. PB0159). Unique
       Identifier : AIDSLINE ICA10/94369606
 AB    OBJECTIVES: Evaluate the therapeutic value of abeclametosone
       hemissuccinate and neomicine in solution, to decrease the symptoms and
       time duration of the recurrent stomatitis aphthous. METHOD: After
       combining both products we studied 50 patients with major aftas and
       herpetic stomatitis. This is a double-blind study to evaluate this
       product. The protocole for patients is to rinse four minutes three times
       a day, after this, the patients can not rinse or cat for 20 minutes.
       RESULTS: The patients treated with the new product showed a great
       improvement after the first mouth-rinse. The symptoms remitted in 48-72
       hours in most patients. CONCLUSIONS: The product is effective for the
       control of the symptoms. We have not found significant side effects in
       its application. We feel the product's viscous formulation is important
       for it facilitates the application adherence to the mucosa and dose
       control by patients.
 DE    AIDS-Related Opportunistic Infections/*DRUG THERAPY
       Beclomethasone/*ADMINISTRATION & DOSAGE  Double-Blind Method  Drug
       Administration Schedule  Drug Therapy, Combination  Human  Mouthwashes
       Neomycin/*ADMINISTRATION & DOSAGE  Recurrence  Stomatitis,
       Aphthous/*DRUG THERAPY  Stomatitis, Herpetic/*DRUG THERAPY  CLINICAL
       TRIAL  MEETING ABSTRACT  RANDOMIZED CONTROLLED TRIAL

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