Document 2978
 DOCN  M94A2978
 TI    Oral mycoplasma and Candida from HIV infected (+) non-AIDS subjects.
 DT    9412
 AU    Rowland RW; Blankenship P; Dobis L; Gunsolley J; Moray L; MCV/VCU,
       Richmond.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):181 (abstract no. PB0151). Unique
       Identifier : AIDSLINE ICA10/94369597
 AB    OBJECTIVE: To assess the subclinical presence of mycoplasma and candida
       in the oral cavity of HIV infected asymptomatic (non-AIDS) patients.
       METHODS: Supra and subgingival plaque samples, hard and soft palate, and
       dorsal tongue swabs were collected from 17 HIV(+) non-AIDS subjects and
       10 HIV(-) controls. No subject presented with a history of fungal
       infections or antifungal chemotherapy. In addition, none had taken
       antibiotics within the past 60 days. Plaque samples were collected from
       an inflamed site and diluted. Swabs were placed into PBS and mixed. All
       specimens were inoculated onto selective and non-selective media and
       incubated appropriately. Venous blood samples were obtained for
       CBC/differential and CD4/CD8 profiles. Oral examinations were performed.
       RESULTS: Candida were isolated from 41% of the HIV(+) subjects, with the
       dorsum of the tongue most common. The HIV(-) control subjects were
       culture negative for candida. Mycoplasma were isolated from 70% of the
       HIV(+) plaque samples and 30% of the HIV(-). CONCLUSIONS: It appears
       that subclinical presence of mycoplasma and candida is higher in
       non-AIDS HIV(+) individuals than in HIV(-) individuals. This subclinical
       presence may be site specific.
 DE    AIDS-Related Opportunistic Infections/DIAGNOSIS/*MICROBIOLOGY
       Candida/ISOLATION & PURIF  Candidiasis, Oral/DIAGNOSIS/*MICROBIOLOGY
       Dental Plaque/MICROBIOLOGY  Human  HIV Seropositivity/*MICROBIOLOGY
       Mycoplasma/ISOLATION & PURIF  Mycoplasma
       Infections/DIAGNOSIS/*MICROBIOLOGY  Support, U.S. Gov't, P.H.S.  MEETING
       ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).