Document 2986
 DOCN  M94A2986
 TI    Incidence of Kaposi's sarcoma among PWAIDS over time: is it decreasing?
       The Spanish Study Group on AIDS and Cancer.
 DT    9412
 AU    Casabona J; Blanch C; Castilla J; Podzamczer D; Riera S; Rubio R;
       Iravessera de les Corts, Barcelona.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):18 (abstract no. 047B). Unique
       Identifier : AIDSLINE ICA10/94369589
 AB    OBJECTIVE: To identify temporal trends of AIDS associated Kaposi's
       sarcoma (KS) in Spain. METHODS: Data from 18.256 AIDS cases reported to
       the Spanish AIDS Registry from 1981 to 1992 and data from a
       retrospective cohort of AIDS patients from three different Autonomous
       Communities (Madrid, Baleares and Catalonia) were used. Follow-up data
       included both clinical outcome and death. A total of 3.945 AIDS patients
       followed for 6.296 person years were included in the cohort. RESULTS:
       Starting in 1985 and for each subsequent year the KS presenting
       percentage was as follows: 14.4, 11.04, 9.28, 6.4, 6.2, 6.0, 6.3 and 6.2
       in 1992. No significant trends were identified after the introduction of
       the 1987 CDC AIDS definition criteria (p = 0.43, 0.35 and 0.29 for all
       cases, IVDUs and homosexual men respectively). Annual incidence rates by
       cohort of diagnosis showed a slight but non significant decrease in the
       first year, but a slight and non significant increase in the second year
       after AIDS diagnosis. DISCUSSION: In our setting, although KS has not
       decreased as an AIDS presenting form, it tends to increase as a
       subsequent AIDS diagnosis. Natural history of HIV have changed, and the
       assessment of KS trends over time should take in account follow-up data
       and specific local features like the prevalence of other opportunistic
       infections, as tuberculosis.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS  Cohort Studies
       Female  Human  Incidence  Male  Retrospective Studies  Sarcoma,
       Kaposi's/*EPIDEMIOLOGY  Spain/EPIDEMIOLOGY  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).