Document 3026
 DOCN  M94A3026
 TI    Epidemiologic approaches: AIDS related Kaposi's sarcoma (KS).
 DT    9412
 AU    Haverkos HW; Drotman DP; NIH, Rockville, MD 20857.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):170 (abstract no. PB0106). Unique
       Identifier : AIDSLINE ICA10/94369549
 AB    OBJECTIVE: We reviewed 12 epidemiologic studies conducted among gay men
       with AIDS to examine the role of potential cofactors in the development
       of KS. METHODS: Aspects of the studies reviewed include basic study
       design, wording of the questionnaires (regarding nitrite inhalant use
       provided by investigators), and published results comparing KS patients
       with those who developed opportunistic infections indicative of AIDS.
       The studies included questions about sociodemographics, medical history,
       use of drugs, travel, and sexual behaviors. Patients were invited to
       provide blood and/or other specimens for laboratory analysis. RESULTS:
       The results of the epidemiologic studies are inconclusive. Nitrite
       inhalant use was a variable often associated with KS (5 studies). The
       differences in outcomes of these studies may reflect differences in
       study designs, sample sizes, timing, quality, and content of interviews
       regarding nitrites, sexual behaviors and other potential cofactors.
       CONCLUSION: The etiology of KS is unknown. Epidemiologic study with
       careful consideration to content of questionnaires and laboratory
       testing may yet reveal the causes or cofactors for this tumor.
 DE    Acquired Immunodeficiency Syndrome/*EPIDEMIOLOGY/TRANSMISSION
       AIDS-Related Opportunistic Infections/EPIDEMIOLOGY/ETIOLOGY  Causality
       Human  Male  Nitrites  Risk Factors  Sarcoma,
       Kaposi's/*EPIDEMIOLOGY/ETIOLOGY  Sex Behavior  Skin
       Neoplasms/*EPIDEMIOLOGY/ETIOLOGY  Substance Use
       Disorders/COMPLICATIONS/EPIDEMIOLOGY  MEETING ABSTRACT

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