Document 3027
 DOCN  M94A3027
 TI    Kaposi's sarcoma: a lymphoscintigraphic study of HIV-infected and
       HIV-seronegative patients.
 DT    9412
 AU    Cestari S da C; Petri V; Castiglioni ML; Alchorne MM; Katiki T; Escola
       Paulista de Medicina, Sao Paulo, Brazil.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):170 (abstract no. PB0108). Unique
       Identifier : AIDSLINE ICA10/94369548
 AB    OBJECTIVE: to evaluate extension of lymphatic involvement/damage in
       cases of Kaposi's sarcoma (KS) of HIV-infected and non HIV-infected
       individuals. A lymphologic perspective is focused to discuss correlation
       between KS genesis and lymphatic disorder(s). METHODS:
       Lymphoscintigraphy (radiolabeled 99mTc-Dextran intradermal injection)
       was performed in three HIV-infected and two non-HIV-infected KS
       patients. The legs of all cases were studied according the sites of KS
       plaques. RESULTS: In all five cases there were clear lymphatic disorder
       connection to KS tumors. The most common findings were: reduced
       lymphatic drainage, collateral flow and dermal reflow. In cases of
       severe lymphoedema lymphatics were not visualized after expected time.
       CONCLUSION: Controversial genesis of KS makes lymphoscintigraphy an
       useful method to study connection(s) between lymphologic disorders and
       KS development. It can be employed to detect non suspected KS tumors, to
       evaluate evolution and to amplify discussion about KS to be a disease of
       lymphatic system.
 DE    Dextrans/DIAGNOSTIC USE  Human  HIV Infections/*RADIONUCLIDE IMAGING
       Injections, Intradermal  Leg  Lymphatic Diseases/*RADIONUCLIDE IMAGING
       Lymphedema/RADIONUCLIDE IMAGING  Organotechnetium Compounds/DIAGNOSTIC
       USE  Prognosis  Sarcoma, Kaposi's/*RADIONUCLIDE IMAGING  Skin
       Neoplasms/*RADIONUCLIDE IMAGING  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).