Document 3055
 DOCN  M94A3055
 TI    Adenosinedeaminase (ADA): indicator of evolution of the HIV infection.
 DT    9412
 AU    Monticelll A; Balbaryski J; Lewi D; Jauregui Rueda H; COINSIDA
       Fundation, Buenos Aires, Argentina.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):164 (abstract no. PB0081). Unique
       Identifier : AIDSLINE ICA10/94369520
 AB    OBJECTIVE: 1) To determine the use of the ADA test as an indicator of
       evolution of the HIV infection. 2) To evaluate the correlation between
       the ADA test and the CD4+ linphocytes count values. 3) Put forward
       values for the ADA test equivalent to CD4+ ones in the CDC
       classification. METHODS: One hundred and ten HIV positive patients; both
       sexes, average age: 28 years old, were studiet; 33 percent of the
       patient studied had some kind of the infection. They were classified
       according to the CDC classification, April 1992; 30 HIV negative
       patients were used as controls for ADA test. The linphocytes CD4+ were
       counted up by flow citometric and the ADA test by colorimetric method.
       RESULTS: TABULAR DATA, SEE ABSTRACT VOLUME. DISCUSSION AND CONCLUSIONS:
       1. The ADA test can be considered as a useful marker of the evolution of
       the infection by HIV. 2. It was observed correlation between ADA test
       and CD4+ linphocytes count taking into account the CDC classification.
       3. ADA values equivalent to the suggested ones by the CDC for the
       CD4+count can be established. 4. In the 2 degree and 3 degree stages, in
       presence of some kind of the TBC, It was observed that the ADA test
       value was 40% above the corresponding one to the stage.
 DE    Adenosine Deaminase/*BLOOD  Adult  AIDS-Related Opportunistic
       Infections/CLASSIFICATION/DIAGNOSIS/  PHYSIOPATHOLOGY  Female  Human
       HIV Infections/CLASSIFICATION/*DIAGNOSIS/PHYSIOPATHOLOGY  Leukocyte
       Count  Male  Prognosis  T4 Lymphocytes/IMMUNOLOGY  MEETING ABSTRACT

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