Document 3109
 DOCN  M94A3109
 TI    The clinical presentation of HIV-1 disease and AIDS at the Chulalongkorn
       University Hospital in Bangkok, Thailand.
 DT    9412
 AU    Ruxrungtham K; Muller O; Teeratakulpisarn S; Sirivichakul S; Ubolyam S;
       Hanvanich M; Phanuphak P; Thai Red Cross Society, Bangkok, Thailand.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):151 (abstract no. PB0032). Unique
       Identifier : AIDSLINE ICA10/94369466
 AB    OBJECTIVE: To describe the clinical dimension of the Thai AIDS epidemic
       with respect to one hospital in Bangkok. METHODS: Retrospective analysis
       of data from 446 consecutive patients attending the AIDS outpatient
       clinic of the Chulalongkorn University Hospital in Bangkok during a 10
       weeks period in 1993/94. RESULTS: Of 446 patients, 81% were male and 19%
       female. Mean age was 32 ys (28 in females). 24% of patients were new to
       the clinic, and 41% came from outside Bangkok. 86% reported
       heterosexual, 9% homo/bisexual, and 5% i.v. drug use risk. 22% were
       asymptomatic or lymphadenopathy syndrome, 31% were ARC, and 47% were
       AIDS by clinical or laboratory (CD4 < 200) definition. The most commen
       manifestations in the clinical history were generalized lymphadenopathy
       (39%), oral symptoms as OHL (45%) or thrush (26%), dermal symptoms as
       pruritic maculopapular eruption (27%), seborrhoic dermatitis (6%),
       bacterial skin infections (8%), H. simplex (4%), or H. zoster (17%),
       chronic fever (10%), chronic diarrhea (9%), severe weight loss (13%),
       tuberculosis (15%), PCP (5%), and cryptococcal meningitis (3%). 30% of
       patients had received antiretroviral treatment before. 15% have been
       hospitalised (mean 17 days) at least once during HIV disease,
       tuberculosis (38%), cryptococcal meningitis (18%) and PCP (16%) being
       the major causes for hospitalisation. CONCLUSIONS: Increasing numbers of
       severely ill patients with HIV disease are seen in Bangkok. Because of
       this being only the start of the clinical epidemic, there is urgent need
       for the development of alternative strategies in treatment and care for
       AIDS in Thailand.
 DE    Acquired Immunodeficiency Syndrome/*EPIDEMIOLOGY/PHYSIOPATHOLOGY/
       TRANSMISSION  Adult  AIDS-Related Complex/EPIDEMIOLOGY/PHYSIOPATHOLOGY
       Female  Human  Male  Retrospective Studies  Sex Behavior  Substance
       Abuse, Intravenous  Thailand/EPIDEMIOLOGY  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
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