Document 3113
 DOCN  M94A3113
 TI    HIV disease: clinical spectrum in state of Gujarat, India.
 DT    9412
 AU    Patel AK; Sheth JT; Vasa CV; Patel RK; Saxena DM; B.J. Medical College &
       Civil Hospital, Ahmedabad, Gujarat, India.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):150 (abstract no. PB0028). Unique
       Identifier : AIDSLINE ICA10/94369462
 AB    OBJECTIVE: Main objective of this study is to explore the clinical
       presentation of HIV disease in State of Gujarat, India. METHODS: The
       patients admitted to our institute with high risk behavior and clinical
       features related to HIV disease were subjected for HIV testing after
       counselling. The study includes only symptomatic individuals with HIV
       disease. All patients were investigated for relevant opportunistic and
       secondary infections. CD4 & CD8 counts were not done as facility is not
       available. RESULTS: Total 31 patients 14 male and 17 female with M:F =
       0.824:1. The mode of transmission being sexual route 18 (58.07%)
       patients (Heterosexual 17 (54.84%), Homosexual 1 (3.23%), Parenteral
       route 13 (41.94%) patients (Blood transfusion 13 (41.94), I.V. drug
       abusers Nil, infected needle injury Nil), and vertical transmission Nil.
       The common modes of presentation were Fever more than 1 month (80.65%)
       weightloss more than 10% of body weight (77.42%). Diarrhoea more than 1
       month (41.94%), Oropharyngeal candidiasis (41.94%), Pulmonary and extra
       Pulmonary tuberculosis (25.81%), Recurrent Pyogenic infections (12.90%),
       generalised lymphadenopathy (12.90%),? Pneumocystis Carinii pneumonia
       (12.90%). AIDS Dementia Complex, (9.68%) and Recurrent Herpes Zoster
       (9.68%) All the symptomatic patients were admitted to general ward,
       treated with general nursing care, proper nutrition and fluid &
       electrolyte maintenance. Specific therapy was given for identified
       opportunistic infections. Antiretroviral therapy in form of Zidovudine
       was given to 3 patients without any clinical improvement. In outcome, 10
       patients died and 21 patients were discharged with advise of regular
       follow up of which 7 patients were lost to follow up and 14 patients are
       regular in follow up. DISCUSSION AND CONCLUSIONS: In India while we are
       expecting explosion of AIDS cases in near future, awareness regarding
       clinical presentation of patients with HIV disease is important. Apart
       from prolonged fever, weightloss and chronic diarrhoea, pulmonary and
       extrapulmonary tuberculosis, oropharyngeal candidiasis, recurrent
       pyogenic infections and generalised lymphadenopathy are the common modes
       of presentation.
 DE    Acquired Immunodeficiency Syndrome/*PHYSIOPATHOLOGY/THERAPY/
       TRANSMISSION  AIDS-Related Opportunistic
       Infections/PHYSIOPATHOLOGY/THERAPY  Female  Homosexuality  Human  HIV
       Infections/*PHYSIOPATHOLOGY/THERAPY/TRANSMISSION  India  Male
       Risk-Taking  Sex Behavior  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
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