Document 3120
 DOCN  M94A3120
 TI    Trace elements in patients with HIV-1 infection.
 DT    9412
 AU    Peraire J; Vidal F; Schuhmacher M; Domingo J; Porras J; Richart C;
       Department of Internal Medicine, Hospital Joan XXIII, Tarragona,; Spain.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):149 (abstract no. PB0022). Unique
       Identifier : AIDSLINE ICA10/94369455
 AB    OBJECTIVE: To provide a detailed characterization of trace elements
       concentrations in patients with HIV-1 infection. METHODS: Serum and
       urinary zinc, selenium, copper, iron, magnesium and manganese
       concentrations were determined in 19 patients AIDS (IVC1, CDC 1987)
       compared to 25 individuals with asymptomatic infection (II, CDC 1987)
       and 18 healthy controls. RESULTS: Serum concentrations are reported in
       the table. There was a significant decrease in the serum selenium levels
       in both groups of HIV infected patients vs controls. No significant
       differences between groups were found in the urinary levels of the trace
       elements. TABULAR DATA, SEE ABSTRACT VOLUME. DISCUSSION AND CONCLUSIONS:
       Patients infected by HIV-1 have marked selenium deficiency. Since some
       have reported that a low level of selenium may have a direct effect on
       T-cell dependent immune function, further studies are justified to
       evaluate the effect of selenium supplements over immune status of HIV-1
       infected patients.
 DE    Acquired Immunodeficiency Syndrome/*BLOOD/URINE  Analysis of Variance
       Comparative Study  Copper/BLOOD  Human  HIV Seropositivity/*BLOOD/URINE
       *HIV-1  Iron/BLOOD  Magnesium/BLOOD  Manganese/BLOOD  Reference Values
       Selenium/BLOOD  Trace Elements/*BLOOD/URINE  Zinc/BLOOD  MEETING
       ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).