Document 3131
 DOCN  M94A3131
 TI    Gastrointestinal parasites and HIV-1 in Ugandan male adults.
 DT    9412
 AU    Mugyenyi P; Tugume S; Lutalo T; Kibende S; Joint Clinical Research
       Centre, Kampala, Uganda.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):147 (abstract no. PB0016). Unique
       Identifier : AIDSLINE ICA10/94369444
 AB    OBJECTIVE: To determine any association between gastro-intestinal tract
       parasites (GITPs) and HIV-1 serostatus among young Ugandan male adults.
       METHOD: Stool and blood samples of 1034 randomly selected males were
       examined for presence of GITPs and HIV-1 sero status respectively. Any
       association between particular GITPs found and HIV status was
       investigated using Chi square tests of association. RESULTS: 307 (29.7%)
       of the study group were HIV-1 sero positive. The most common parasites
       found were Hookworm (26.9%), S. mansoni (5.4%), E. vermicularis (3.9%),
       T. Tricuris (3.2%) and S. stercolaris (2.5%). There was a significant
       association between present/absence of Hookworm and HIV-1 sero status (p
       = 0.004). No other association was found. CONCLUSION: The data suggests
       an association between HIV-1 positivity and Hookworm infestation. As
       Hookworm infestation and HIV-1 presence are highest in the tropics, such
       an association may be a co-factor and adversely affect progression to
       AIDS. This relationship and other intestinal parasites need to be
       investigated.
 DE    Adult  Gastrointestinal Diseases/COMPLICATIONS/EPIDEMIOLOGY/
       *PARASITOLOGY  Hookworm Infections/COMPLICATIONS/EPIDEMIOLOGY  Human
       HIV Seropositivity/*COMPLICATIONS  *HIV-1  Male  Parasitic
       Diseases/*COMPLICATIONS/EPIDEMIOLOGY  Random Allocation
       Schistosomiasis/COMPLICATIONS/EPIDEMIOLOGY  Uganda  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).