Document 3132 DOCN M94A3132 TI The prevalence of slow progressors in HIV-1 infection in Galicia, Spain. DT 9412 AU Castro A; Hermida M; Pereiro C; Lopez Calvo MS; Ruanova S; Moreno J; Pedreira J; Internal Medicine Service, Hospital Juan Canolejo, La Coruna. SO Int Conf AIDS. 1994 Aug 7-12;10(1):146 (abstract no. PB0011). Unique Identifier : AIDSLINE ICA10/94369443 AB ++OBJECTIVES: To analyse the prevalence of patients with slow progressor criteria (SP) (patients infected > 5 years and CD4 counts > 500/mm3 with no antirretrovirical treatment) in HIV-1 in the La Coruna area of 500,000 inhabitants (Galicia, Northwestern Spain). METHODS: 804 HIV-1 positive patients were studied between 1984 and 1994 in our hospital; 581 men and 223 women with a mean age of 26.9 + 0.25 years. Risk factors were: 80.7% intravenous drug abusers, 5.8% heterosexual transmission, 2.7% homo/bisexual, 0.8% post-transfussional, 10% others. Average study period 2.96 years (range: 30 days-10.07 years) 302 were AIDS cases. RESULTS: The global prevalence of SP patients was 17/804 (2.1%); 17/133 (12.7%) in those followed for > 5 years. 12 were men and 5 women, with a mean age of 24.3 + 1.29 years. All of them were intravenous druf abusers, followed for 5.48 years (range: 5.08 + 10.07); mean CD4 cell count was initially 1146 + 124/mm3 and finally 1009 + 92/mm3. There were no epidemiological difference with non slow progressors patients. CONCLUSIONS: 1. The prevalence of slow progressors HIV-1 patients is low in Galicia. 2. All slow progressors patients were intravenous drug abusers. 3. CD4 cell counts remained stable in all slow progressors patients during follow-up. DE Adult Blood Transfusion Female Follow-Up Studies Human HIV Seropositivity/*EPIDEMIOLOGY/IMMUNOLOGY/*PHYSIOPATHOLOGY Male Prevalence Risk Factors Sex Behavior Spain/EPIDEMIOLOGY Substance Abuse, Intravenous Time Factors T4 Lymphocytes/IMMUNOLOGY MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).