Document 3135
 DOCN  M94A3135
 TI    Clinical and pathological aspect of HIV-sero positive inpatients.
 DT    9412
 AU    Okubo T; Fujita H; Soga T; Mohri H; Nagashima Y; Misugi K; Ichikawa S;
       Soda K; 1st Dept. Int. Med., Yokohama City Univ. School of Medicine,;
       Japan.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):146 (abstract no. PB0012). Unique
       Identifier : AIDSLINE ICA10/94369440
 AB    OBJECTIVES: To describe the clinico-pathological aspect of HIV/AIDS
       inpatients. METHODS: We reviewed HIV/AIDS inpatients in our hospital
       since 1988. We examined risk factor, CD4 counts, CD4/8 ratio, cause of
       death and the survival time after diagnosis of AIDS. RESULTS: A total of
       13 HIV sero-positive subjects were admitted to our hospital, including
       11 cases (85%) with AIDS. One patient was a foreigner. All cases were
       male; age range 18-70 years (median 30 years). Hemophiliacs and sexually
       transmitted patients account for 62% and 38% of cases, respectively.
       There were no cases of intravenous drug users. In all cases with AIDS,
       CD4+ cells and CD4/8 ratio significantly decreased with median value of
       78/micron and 0.19, respectively. Five cases (45%) were deceased;
       interstitial pneumonia (2), HIV associated nephropathy (1), AIDS
       dementia (1), malignant lymphoma (1). Findings of autopsy done in three
       cases revealed systemic various infection, including Pneumocystis
       carini, cytomegalovirus and candida. The median survival time after
       diagnosis of AIDS were 26 months. DISCUSSION AND CONCLUSIONS: We
       controlled approximately 25% of the total AIDS cases in Kanagawa
       prefecture. In Japan, hemophiliacs occupies the largest share in
       HIV/AIDS cases, while sexual transmission increased, recently. We assume
       hospitalized patients in Japan are rather small in number compared with
       those in other countries.
 DE    Acquired Immunodeficiency Syndrome/MORTALITY/*PHYSIOPATHOLOGY/
       TRANSMISSION  Adolescence  Adult  Aged  Cause of Death  CD4-CD8 Ratio
       Human  HIV Seropositivity/MORTALITY/*PHYSIOPATHOLOGY/TRANSMISSION
       Inpatients  Male  Middle Age  Retrospective Studies  Survival Analysis
       T4 Lymphocytes/IMMUNOLOGY  MEETING ABSTRACT

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