Document 3143
 DOCN  M94A3143
 TI    Demographics and survival in urban adults with HIV disease.
 DT    9412
 AU    Chaisson RE; Keruly J; Moore RD; Johns Hopkins Univ., Baltimore, MD.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):144 (abstract no. PB0001). Unique
       Identifier : AIDSLINE ICA10/94369432
 AB    OBJECTIVE: To compare survival patterns in a demographically mixed
       population of patients with HIV disease from an urban area. METHODS:
       Patients registered in an urban HIV Clinic were followed observationally
       for a mean of 15 months (median 12) from entry. Survival was analyzed by
       selected demographic factors and CD4 counts. Cox proportional hazards
       modelling was used to identify predictors of death. RESULTS: The cohort
       consists of 895 patients. Patients are 69% male, 31% female, 78% black,
       20% gay-bisexual, 49% IDU, and 31% heterosexual risk. Entry CD4 counts
       were < 50 in 19%, 50-200 in 18%, 201-500 in 36%, and > 500 in 28%.
       During followup, 165 patients (18%) died. Mortality was 50% for CD4 <
       50, 34% for CD4 50-200, and 5% for CD4 > 200 (p < .0001). For patients
       with entry CD4 < 200, median survival was 649 days for men and 621 days
       for women. The hazard of death was not increased for women (RH .96) or
       IDUs (RH 1.2). Entry CD4 < 50 was strongly associated with death (RH
       9.1, p < .0001), as was entry CD4 50-200 (RH 2.2, p < .0001).
       CONCLUSION: In this heterogeneous urban cohort, demographic factors were
       not associated with death from HIV. CD4 counts were the strongest
       predictors of survival and have similar utility in men and women.
 DE    Adult  Baltimore/EPIDEMIOLOGY  Bisexuality  Blacks  Cohort Studies
       Comparative Study  Demography  Female  Homosexuality  Human  HIV
       Infections/IMMUNOLOGY/*MORTALITY  Male  Prognosis  Proportional Hazards
       Models  Risk Factors  Sex Behavior  Sex Factors  Substance Abuse,
       Intravenous  Survival Rate  T4 Lymphocytes/IMMUNOLOGY  Urban
       Population/*STATISTICS & NUMER DATA  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
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