Document 3184
 DOCN  M94A3184
 TI    Evaluation of HTLV-I infection in healthy Nikkei population of
       Lima-Peru.
 DT    9412
 AU    Gotuzzo E; Yamamoto V; Kanna M; Chauca G; Philipps I; Watts D; AvH,
       UPCH, Lima-Peru.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):134 (abstract no. PA0155). Unique
       Identifier : AIDSLINE ICA10/94369391
 AB    HTLV-I infection has been recognized as endemic in Japan, the Caribbean
       and recently in Colombia and Peru. The Japanese migration to Peru
       started more than 100 years ago and there is an important colony of
       Japanese descendants in Lima. OBJECTIVE: To evaluate the rate of
       infection by HTLV-I in healthy people of exclusively Japanese
       ascendency, coming to the Peruvian-Japanese Medical Center. METHODS: The
       cases were ELISA and WB positive. All of them gave their Informed
       Consent. The population was distributed according to several criteria.
       RESULTS: Four hundred and eleven persons were studied. Four of them had
       positive ELISA tests plus an indetermined WB, and were excluded; 23/407
       (5.65%) were both Elisa and WB positive, 19/280 (6.8%) women and 4/127
       (3.1%) men. Distribution: By Age: 0/91 (< 40 years), 5/135 (40-59
       years), 12/160 (60-79 years) and 6/21 (> 80 years) were positive; the
       difference was significant. By generation: migrants from Japan 13/81
       (16%); first generation (Japanese parents) 10/247 (4.0%); second
       generation (Japanese grandparents) 0/88 (p < 0.05). By place of origen
       in Japan: Okinawa 20/213 (9.4%); elsewhere 3/198 (1.5%), p < 0.05.
       CONCLUSION: HTLV-I infection occurs in nikkei population, basically in
       those born in Okinawa. In the nisei and san-sei population, the rate of
       infection is progressively less.
 DE    Adult  Age Factors  Aged  Blotting, Western  Comparative Study
       Enzyme-Linked Immunosorbent Assay  Geography  Human  HTLV-I
       Antibodies/*BLOOD  HTLV-I Infections/DIAGNOSIS/*EPIDEMIOLOGY/IMMUNOLOGY
       Japan/ETHNOLOGY/EPIDEMIOLOGY  Middle Age  Peru/EPIDEMIOLOGY  Reference
       Values  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).