Document 3188 DOCN M94A3188 TI Epidemiological study on HTLV-II infection among Colombian native indians. DT 9412 AU Fujiyama C; Fujiyoshi T; Yashiki S; Tajima K; Hayami M; Zaninovic V; Sonoda S; Department of Virology, Faculty of Medicine, Kagoshima; University, Japan. SO Int Conf AIDS. 1994 Aug 7-12;10(1):133 (abstract no. PA0153). Unique Identifier : AIDSLINE ICA10/94369387 AB OBJECTIVE: Co-infection with HIV and human T-cell lymphotropic virus type II (HTLV-II) is known to be prevalent among intravenous drug users (IVDUs). There are some reports indicating that HTLV-II may modify the HIV infection, while it is not clear the natural history of HTLV-II and effects of HTLV-II on prognosis of HIV infection. In order to know natural history of HTLV-II infection and their distribution, we conducted epidemiological study on HTLV-II infection among Colombian native Indians. METHODS: We screened 215 plasma samples of 2 different ethnic groups (Guahibo and Wayuu Indians) for the antibodies against HTLV-I/II and HIV with particle agglutination (PA) test. Seropositivities of HTLV-I or HTLV-II were differentiated by HTLV type specific western blot (WB). RESULTS: HTLV-II carriers were found in Guahibo Indians (29/92, 31.5%) and Wayuu Indians (5/123, 4.1%). There was no case infected with HIV. HTLV-II seroprevalence in females showed age-dependent increase. DISCUSSION AND CONCLUSION: We found high endemic foci of HTLV-II among Colombian native Indians. These subjects are useful to study on natural history and pathogenesis of HTLV-II infection as well as the effects of HTLV-II on HIV co-infection. DE Age Factors Agglutination Tests Colombia/EPIDEMIOLOGY Ethnic Groups Female Human HIV Infections/COMPLICATIONS/EPIDEMIOLOGY HTLV-I Antibodies/BLOOD HTLV-II Antibodies/BLOOD HTLV-II Infections/COMPLICATIONS/DIAGNOSIS/*EPIDEMIOLOGY Indians, South American/*STATISTICS & NUMER DATA Male Prevalence Sex Factors MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).