Document 3214
 DOCN  M94A3214
 TI    Opportunistic infections in HIV-2 infected patients in Dakar (Senegal).
 DT    9412
 AU    Sow PS; Faye MA; Diouf G; Coll-Seck AM; Infectious Diseases Department,
       Fann Hospital, Dakar.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):127 (abstract no. PA0128). Unique
       Identifier : AIDSLINE ICA10/94369361
 AB    OBJECTIVES: (1) To identify the opportunistic infections in HIV-2
       infected patients in Dakar. (2) To compare clinical manifestations in
       HIV-2 infected patients with HIV-1. METHODOLOGY: It is a case-control
       study from January 1986 to June 1993. Inclusion criteria were: patients
       with manifestations of HIV infection according to the clinical Bangui
       classification (WHO 1985) and serology positive in Western-blot.
       RESULTS: 181 HIV-1 and 58 HIV-2 infected patients were enrolled in this
       study. The mean age of HIV-2 and HIV-1 infected patients is 39 years +/-
       9.95 (SD) and 33 years +/- 9.17 (SD) respectively. The sex-ratio
       (male/female) is 3.2 for HIV-2 and 2.0 for HIV-1. Opportunistic
       infections in these patients were: tuberculosis (HIV-2: 24.1%, HIV-1:
       39.7%, p < 0.05); chronic diarrhea (HIV-2: 74.1%, HIV-1: 63.5%, p =
       0.15); oral candidasis (HIV-2: 79.3%, HIV-1: 87.8%, p = 0.10); atypical
       pneumonia (HIV-2: 31%, HIV-1: 29.8%, p = 0.92); Kaposi sarcoma (HIV-2:
       5.1%, HIV-1: 5.5%, p = 0.90); Herpes zoster (HIV-2: 1.7%, HIV-1: 5.5%, p
       = 0.20). CONCLUSION: The classic opportunistic infections in HIV-1
       patients are also seen in HIV-2 patients at the stage of AIDS. Only
       tuberculosis is more frequently seen in HIV-1 than HIV-2 patients. HIV-2
       is not less lisky for opportunistic infections than HIV-1 at the stage
       of AIDS.
 DE    Acquired Immunodeficiency Syndrome/COMPLICATIONS  Adult  AIDS-Related
       Opportunistic Infections/*CLASSIFICATION/  EPIDEMIOLOGY  Candidiasis,
       Oral/EPIDEMIOLOGY  Case-Control Studies  Chronic Disease  Comparative
       Study  Diarrhea/EPIDEMIOLOGY  Female  Herpes Zoster/EPIDEMIOLOGY  Human
       *HIV-1  *HIV-2  Male  Pneumonia/EPIDEMIOLOGY  Risk Factors  Sarcoma,
       Kaposi's/EPIDEMIOLOGY  Senegal  Tuberculosis/EPIDEMIOLOGY  MEETING
       ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).