Document 0081
 DOCN  M9440081
 TI    Thoracic AIDS-related lymphoma:CT appearance and CD4 counts (Meeting
       abstract).
 DT    9404
 AU    Sider L; Melany M; Chicago, IL
 SO    Am J Roentgenol; 160(4, Suppl):97 1993. Unique Identifier : AIDSLINE
       ICDB/94697401
 AB    It is now well recognized that AIDS-related lymphoma (ARL) usually
       presents as extranodal disease different from lymphoma in
       immune-competent patients (pts). In this series, we will review our
       experience in an 8-yr period in order to detect the most frequent
       presentations of thoracic ARL. In addition, further correlation will be
       made with the pts' CD4 counts to determine if, at different levels of
       cellular immunity, one presentation predominates. Materials and methods:
       Chest CT scans and medical records of 36 pts with biopsy proven thoracic
       ARL were evaluated. The series included 344 male and 2 female pts
       ranging in age from 22 to 52 yr. All pts' CD4 counts were obtained
       within 2 wk of diagnosis. Results: The majority of pts presented with
       more than one site of thoracic involvement. The two most common findings
       were pleural effusion and axillary adenopathy, each occurring in 14 of
       36 pts (39%). Pulmonary parenchymal nodules were identified in 13 pts
       (36%). Eight pts (22%) demonstrated an interstitial pattern of lung
       disease and only 2 pts (6%) had alveolar infiltrates as a manifestation
       of their disease. Mediastinal adenopathy was seen in 7 pts (19%) and
       hilar adenopathy in only 3 pts (8%). Conclusion: Extranodal involvement
       in thoracic ARL is confirmed in our series of 36 pts with pleural
       effusion and parenchymal processes predominating. When adenopathy was
       present it most frequently involved unsuspected axillary nodes. Findings
       were often multiple in each pt. We will further correlate the different
       CT findings with CD4 counts in order to determine if, given a particular
       CD4 count and specific pathologic finding on CT, one can more
       confidently suggest the diagnosis of ARL.
 DE    Adult  Antigens, CD4/*ANALYSIS  Female  Human  Lymphoma,
       AIDS-Related/COMPLICATIONS/IMMUNOLOGY/*RADIOGRAPHY  Male  Middle Age
       Pleural Effusion/COMPLICATIONS  Thoracic
       Neoplasms/IMMUNOLOGY/*RADIOGRAPHY  Tomography, X-Ray Computed  MEETING
       ABSTRACT

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