Document 0103
 DOCN  M9440103
 TI    [HTLV-I and retinal antigen recognized by T cells]
 DT    9404
 AU    Fukushima A; Ueno H; Fujimoto S; Department of Ophthalmology, Kochi
       Medical School, Japan.
 SO    Nippon Ganka Gakkai Zasshi. 1994 Feb;98(2):157-61. Unique Identifier :
       AIDSLINE MED/94152519
 AB    MT-2 immune but not naive murine (B10.BR) spleen cells responded not
       only to HTLV-I-infected cell lines but also to retinal antigens of
       various species by antigen-induced cell proliferation. The phenotype of
       the responding cells against HTLV-I-infected cell lines as well as
       retinal antigens was Thy-1.2+, CD4+ and CD8-. The antigen-induced cell
       proliferation against both HTLV-I-infected cell lines and retinal
       antigens was clearly inhibited by monoclonal antibodies to CD3, CD4, and
       MHC class II (I-AK). These data indicate that an epitope of
       HTLV-I-infected cell lines recognized by the CD4+ T cell is
       crossreactive to that of retinal antigens.
 DE    Animal  Antigenic Determinants/IMMUNOLOGY  Antigens/*IMMUNOLOGY  Cell
       Line  Cross Reactions  English Abstract  Female  HTLV-I
       Antigens/*IMMUNOLOGY  Mice  Mice, Inbred Strains  Retina/*IMMUNOLOGY
       Species Specificity  Specific Pathogen-Free Organisms  T4
       Lymphocytes/*IMMUNOLOGY  JOURNAL ARTICLE

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