Document 0133
 DOCN  M9440133
 TI    [Determinants of the prevalence of hepatitis B viral infection in
       parenteral drug abusers]
 DT    9404
 AU    Torrella Ramos A; Hernandez Aguado I; Santos Rubio C; Fernandez Garcia
       E; Garcia de la Hera M; Avino Rico MJ; Conselleria de Sanitat y Consum,
       Centros de Informacion y; Prevencion de SIDA (CIPS) de Castellon,
       Valencia, Alicante.
 SO    Rev Clin Esp. 1993 Dec;193(9):475-9. Unique Identifier : AIDSLINE
       MED/94151519
 AB    In order to study the frequency of hepatitis B viral infection and its
       determinants, we studied 2337 intravenous drug users who visited three
       AIDS information and prevention centers between 1987 and 1991. The
       presence of three markers for HBV (AntiHBc, AntiHBs, and AgHBs) and of
       HIV-1 antibodies was analyzed. A structured questionnaire was used to
       gather data on sociodemographic information and risk factors for
       infection. The prevalence of HBV infection (at least one positive
       marker) was 78% (95% CI: 76%-80%). After adjustment via logistic
       regression, duration of drug addiction (OR-5.04), the number of sexual
       partners (OR = 1.70), and the presence of antibodies for HIV-1 (OR =
       2.44) were associated with increased HBV infection were higher level of
       education (OR = 0.67) and residence in a smaller city (OR = 0.66). The
       marginalization of the practice of drug use makes prevention activities
       very difficult, and by the time they use health services, the majority
       of users have already been in contact with HBV. Other infectious agents
       which share parenteral transmission can reach a similar prevalence if
       preventive efforts are not intensified.
 DE    Adult  Chi-Square Distribution  English Abstract  Female  Hepatitis
       B/*EPIDEMIOLOGY/IMMUNOLOGY  Hepatitis B Antibodies/BLOOD  Hepatitis B
       Antigens/BLOOD  Human  Logistic Models  Male  Odds Ratio  Prevalence
       Seroepidemiologic Methods  Socioeconomic Factors  Spain/EPIDEMIOLOGY
       Substance Abuse, Intravenous/*COMPLICATIONS/EPIDEMIOLOGY  Support,
       Non-U.S. Gov't  Urban Population/STATISTICS & NUMER DATA  JOURNAL
       ARTICLE

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