Document 0134
 DOCN  M9440134
 TI    Lymph node pathology in Zimbabwe: a review of 2194 specimens.
 DT    9404
 AU    Sibanda EN; Stanczuk G; Regional Immunology Department, Birmingham
       Heartlands Hospital,; UK.
 SO    Q J Med. 1993 Dec;86(12):811-7. Unique Identifier : AIDSLINE
       MED/94151469
 AB    When the body's defences are breached by infection, information about
       such an event is channelled through the lymphatic system to the lymphoid
       organs in which immune responses occur. The key participants in these
       responses are lymphocytes, which populate the lymph nodes, spleen, and
       mucosal lymphoid tissues. Together with other cells, they form an
       architecture and cell network that enables coordinated function. The
       lymph nodes, which are usually superficial, are easily accessible and
       therefore frequently sampled by clinicians. The findings on such samples
       are invaluable in the diagnosis, staging, treatment and prognosis of
       disease. From the 28,895 histology specimens submitted to the
       Histopathology unit in Harare, Zimbabwe in the period January 1988 to
       June 1990, we have selected and reviewed all lymph node biopsy reports.
       The commonest diseases in the 2194 lymph node specimens submitted were:
       (a) non specific hyperplasia (33%); (b) tuberculous lymphadenitis
       (26.7%); (c) metastases (12.4%); (d) Kaposi's sarcoma (9%); (e)
       lymphomas (7%). The trends for nodal tuberculosis (including
       hyporeactive tuberculous lymphadenitis), Kaposi's sarcoma, florid
       follicular hyperplasia and lymphomas are discussed in the context of the
       increased incidence of HIV-related lymphoadenopathy.
 DE    Adolescence  Adult  Age Distribution  Aged  Aged, 80 and over  Child
       Child, Preschool  Female  Human  Hyperplasia  Infant  Infant, Newborn
       Lymph Nodes/PATHOLOGY  Lymphadenitis/EPIDEMIOLOGY  Lymphatic
       Diseases/*EPIDEMIOLOGY/PATHOLOGY  Lymphatic Metastasis  Male  Middle Age
       Sarcoma, Kaposi's/EPIDEMIOLOGY  Sex Distribution  Tuberculosis, Lymph
       Node/EPIDEMIOLOGY  Zimbabwe/EPIDEMIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).