Document 0224
 DOCN  M9440224
 TI    Risk factors for woman-to-man sexual transmission of the human
       immunodeficiency virus. Italian Study Group on HIV Heterosexual
       Transmission.
 DT    9404
 AU    Nicolosi A; Musicco M; Saracco A; Lazzarin A; Department of Epidemiology
       and Medical Informatics, University of; Milan, IRCCS Ospedale S.
       Raffaele, Italy.
 SO    J Acquir Immune Defic Syndr. 1994 Mar;7(3):296-300. Unique Identifier :
       AIDSLINE MED/94149565
 AB    A cross-sectional study of stable monogamous couples, recruited from 16
       clinical and surveillance centers in Italy between 1987 and 1992, was
       carried out to investigate the risk factors of woman-to-man sexual
       transmission of human immunodeficiency virus (HIV). The male partners of
       all HIV-infected women attending the centers were invited to participate
       in the study. Of the 275 male partners who were tested for HIV and
       interviewed with use of a structured questionnaire, 51 were excluded
       because they had other possible risk factor for HIV infection, no
       established risk factor was found in the index case, or they had stopped
       engaging in sexual intercourse. Fourteen of the 224 men (6.3%) were
       seropositive for HIV. At logistic regression, the highest risks of
       transmission were for men practicing peno-anal intercourse [odds ratio
       (OR), 4.6; 95% confidence interval (CI), 1.0-22.2] and for men whose
       partner had acquired immune deficiency syndrome (AIDS) or a CD4+
       lymphocyte count of < or = 400/mm3. No seropositive men were observed
       among those who were aware of the woman's HIV seropositivity since the
       beginning of the relationship or were partners of a zidovudine-treated
       woman. The results suggest that the risk factors described in
       man-to-woman and man-to-man HIV sexual transmission also operate in
       woman-to-man transmission.
 DE    Adult  Blood Transfusion  Condoms  Confidence Intervals  Cross-Sectional
       Studies  Female  Human  HIV Infections/EPIDEMIOLOGY/*TRANSMISSION  HIV
       Seropositivity/EPIDEMIOLOGY  Interviews  Male  Odds Ratio  Prevalence
       Risk Factors  *Sex Behavior  *Sexual Partners  Sexually Transmitted
       Diseases/*TRANSMISSION  Substance Abuse, Intravenous/COMPLICATIONS
       Support, Non-U.S. Gov't  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).