Document 0371
 DOCN  M9440371
 TI    Declining efficacy of AIDS case list cross-referencing in human
       immunodeficiency virus look-back: 1981 through 1992.
 DT    9404
 AU    Samson SM; Edmiston RK; Busch MP; Perkins HA; Irwin Memorial Blood
       Centers, University of California, San; Francisco.
 SO    Transfusion. 1994 Feb;34(2):147-51. Unique Identifier : AIDSLINE
       MED/94143944
 AB    BACKGROUND: The impact of AIDS case list cross-referencing in human
       immunodeficiency virus look-back was assessed. STUDY DESIGN AND METHODS:
       Post-1977 blood donations from former donors identified by 11
       collaborating health departments as having developed AIDS have been
       traced at Irwin Memorial Blood Centers since 1983. To assess the
       changing efficacy of AIDS case list cross-referencing in identifying
       infected donors and recipients, trends in cases reported through
       December 1992 were analyzed. RESULTS: Previous donors (n = 638) were
       identified from 21,917 AIDS case listings, for an overall match rate of
       2.9 percent. The rate of detection of previous donors from listings of
       AIDS cases declined from a peak of 5.3 percent in 1985 to 1.6 percent in
       1992. Overall, 86 percent (1824/2122) of donations by persons later
       reported on AIDS case lists were made prior to January 1983 when risk
       exclusion measures were initiated. Of the 212 known infected recipients
       linked to AIDS case list donors, 87 (41%) were previously identified by
       other look-back approaches. The rate of identification of infected
       recipients detected exclusively through AIDS case listings declined from
       a mean of 21 per year from 1984 to 1987 to a mean of 3 per year from
       1990 to 1992. No transmissions have been documented from donations prior
       to 1979. CONCLUSION: These findings demonstrate the declining yield of
       AIDS case list cross-referencing as a trigger for human immunodeficiency
       virus look-back. Continued reevaluation of look-back programs is
       essential so that their various components may be curtailed when
       justified.
 DE    Acquired Immunodeficiency Syndrome/*EPIDEMIOLOGY/*TRANSMISSION  *Blood
       Donors  *Blood Transfusion  Human  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
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