Document 0518
 DOCN  M9440518
 TI    Screening of blood donations for HIV-1 antibody: 1985-1991.
 DT    9404
 AU    Gunson HH; Rawlinson VI; North Western Regional Transfusion Centre,
       Manchester.
 SO    CDR (Lond Engl Rev). 1991 Dec 6;1(13):R144-6. Unique Identifier :
       AIDSLINE MED/94138434
 AB    One hundred and ninety HIV-1 antibody positive donors have been
       detected, out of 14.85 million blood donations screened in the United
       Kingdom and the Isle of Man, since the start of testing in October 1985
       to the end of March 1991. There were 145 men and 45 women, with an
       overall seropositivity rate of 0.001%. Records for new donors (ie, those
       donating for the first time) have been kept since February 1986 and 79
       out of 1.9 million donations have been seropositive (58 men and 21
       women); a rate of 0.004%. One hundred and forty-one (74.2%) of the 190
       positive donors were found to have been exposed to a high risk of HIV
       infection. Twenty-four (13%) denied any exposure other than heterosexual
       intercourse with partners who were not considered to be at high risk. In
       six cases the partners were from countries where the main route of
       transmission is heterosexual. Seven donors (4%) attributed infection to
       some other cause. Eighteen (9.5%) have been lost to follow-up, are still
       being investigated or have not yet been interviewed. Combined tests
       which screen for both HIV-1 and HIV-2 antibodies were introduced in June
       1990. The last 2.55 million donations (including 370,000 new donors)
       have been tested with these kits. One HIV-2 antibody positive donation
       had been confirmed in a new donor by the end of March 1991.(ABSTRACT
       TRUNCATED AT 250 WORDS)
 DE    Adult  *Blood Donors  England/EPIDEMIOLOGY  Female  Human  HIV
       Antibodies/*ANALYSIS  HIV Infections/*PREVENTION & CONTROL/TRANSMISSION
       HIV Seropositivity/EPIDEMIOLOGY/TRANSMISSION  HIV-1/*IMMUNOLOGY
       HIV-2/*IMMUNOLOGY  Male  *Mass Screening  Risk Factors  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).