Document 0547
 DOCN  M9440547
 TI    Cytomegalovirus retinitis: diagnosis and treatment [editorial]
 DT    9404
 AU    Maclean H; Dhillon B
 SO    Int J STD AIDS. 1993 Nov-Dec;4(6):322-5. Unique Identifier : AIDSLINE
       MED/94137865
 AB    Cytomegalovirus (CMV) is a non-pathogenic organism in the
       immunocompetent, but is a major cause of morbidity and mortality amongst
       patients with AIDS, and the retina is the commonest site of infection.
       If left untreated, patients with CMVR will develop disease in their
       second eye and ultimately become blind. However, with correct diagnosis
       and treatment useful vision can be maintained in the majority of cases.
       Fifteen to 20% of patients with AIDS will contract cytomegalovirus
       retinitis (CMVR) and this may be the AIDS-defining diagnosis though more
       commonly it occurs months after the diagnosis of AIDS. Given the
       increasing number of HIV positive patients and their longer survival, it
       is likely that CMVR will become an increasingly prevalent condition. In
       these patients loss of sight from CMVR has devastating consequences in
       terms of loss of independence and quality of life and therefore
       ophthalmologists and physicians should be aware of the presenting
       characteristics of CMVR, be familiar with therapy and its complications,
       and be able to recognize relapsing infection.
 DE    Antiviral Agents/*ADVERSE EFFECTS  Cytomegalovirus
       Retinitis/DIAGNOSIS/*DRUG THERAPY/PREVENTION &  CONTROL  Human  Mass
       Screening  EDITORIAL  REVIEW  REVIEW, TUTORIAL  JOURNAL ARTICLE

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       protected by Copyright Law (Title 17, U.S.Code).