Document 0622
 DOCN  M9440622
 TI    [Meningoradiculitis disclosing T-lymphocyte leukemia in HTLV-1
       infection]
 DT    9404
 AU    Visy JM; Vassel P; Chaine P; Woimant F; Dumas JL; Lhote F; Mainguene C;
       Haguenau M; Service de Neurologie, Hopital Lariboisiere, Paris.
 SO    Rev Neurol (Paris). 1993;149(6-7):428-31. Unique Identifier : AIDSLINE
       MED/94135118
 AB    A case of HILV1-associated adult T cell leukaemia/lymphoma (ATLL) in a
       21-year olf African woman is reported. The patient presented with
       lymphomatous meningoradiculopathy. The usual clinical features of ATLL
       were absent. Lumbar MRI showed a pial enhancement by DTPA-gadolinium of
       the conus medullaris which extended to the proximal cauda equina. Under
       systemic chemotherapy coupled with intrathecal chemotherapy the patient
       progressively improved, and at the second MRI examination complete
       disappearance of the lumbar enhancement was observed. MRI of the brain
       using axial and coronal T2-weighted sequences detected multifocal
       lesions of high-intensity signal in the subcortical white matter. ATLL
       is unusual in people of African origin. The ATLL-strongyloides
       infestation association has previously been reported, suggesting that
       parasitic infestation may be an important co-factor leading to the
       development of ATLL.
 DE    Adult  Case Report  English Abstract  Female  Human  Leukemia-Lymphoma,
       T-Cell, Acute, HTLV-I-Associated/CEREBROSPINAL  FLUID/*COMPLICATIONS
       Magnetic Resonance Imaging  Meningitis, Viral/CEREBROSPINAL
       FLUID/*ETIOLOGY  Radiculitis/DIAGNOSIS/*ETIOLOGY
       Strongyloidiasis/COMPLICATIONS  JOURNAL ARTICLE

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