Document 0637 DOCN M9440637 TI Mycobacterial infections. DT 9404 AU Peloquin CA; Infectious Disease Pharmacokinetics Laboratory, National Jewish; Center for Immunology and Respiratory Medicine, Denver, Colorado; 80206. SO Pharmacotherapy. 1993 Nov-Dec;13(6):634-9. Unique Identifier : AIDSLINE MED/94134527 AB Infection due to Mycobacterium tuberculosis continues to plague humanity. In the United States, conditions have taken a decided turn for the worse, with an increasing frequency of infection and the spread of multiple-drug-resistant strains. A number of strategies are available to improve the management of this epidemic. Mycobacterium avium is now recognized as a significant cause of morbidity and mortality in patients with the acquired immunodeficiency syndrome. Therapy is limited due to relative drug resistance, drug intolerance, and drug malabsorption; however, potentially useful regimens are being developed. DE Antitubercular Agents/*THERAPEUTIC USE AIDS-Related Opportunistic Infections/*DRUG THERAPY Drug Resistance, Microbial Human Mycobacterium avium Complex/*DRUG EFFECTS Mycobacterium avium-intracellulare Infection/*DRUG THERAPY/ MORTALITY Mycobacterium tuberculosis/*DRUG EFFECTS Tuberculosis/*DRUG THERAPY/EPIDEMIOLOGY/MICROBIOLOGY United States/EPIDEMIOLOGY JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).