Document 0688
 DOCN  M9440688
 TI    Persistent arthralgia and its association with HIV infection in Rwanda.
 DT    9404
 AU    Saraux A; Taelman H; Clerinx J; Batungwanayo J; Kagame A; Kabagabo L;
       Bogaerts J; Van de Perre P; Le Goff P; Department of Internal Medicine,
       Centre Hospitalier de Kigali,; Rwanda.
 SO    J Acquir Immune Defic Syndr. 1994 Feb;7(2):158-62. Unique Identifier :
       AIDSLINE MED/94133086
 AB    A prospective study of persistent arthralgia was carried out on 331
       consecutive female patients admitted to the Department of Internal
       Medicine of the Centre Hospitalier de Kigali in Kigali, Rwanda. The aim
       of this study was to determine its association with HIV-1 infection and
       to describe its clinical characteristics. Ten additional
       HIV-1-seropositive patients with this condition attending the outpatient
       clinic were also included in the clinical study. Persistent arthralgia
       was significantly more common in HIV-1-seropositive hospitalized
       patients (14 of 209, 6.7%) than in HIV-1-seronegative hospitalized
       patients (one of 122, 0.8%; p = 0.02) and had a specificity and a
       positive predictive value for HIV-1 infection of 99.1% and 93.3%,
       respectively. HIV-1-related persistent arthralgia, studied in 24
       patients in early as well as late stages of HIV-1 infection, commonly
       affected several and mainly large joints, was mostly distributed
       symmetrically, and was usually relieved with nonsteroidal
       antiinflammatory drugs. Recurrencies were noted in eight patients. In
       areas highly endemic for HIV-1, persistent arthralgia should be
       considered a probable manifestation of HIV-1 infection, and although it
       is uncommon, it can be regarded as a predictor of HIV-1 infection.
 DE    Adult  Female  Follow-Up Studies  Human  HIV
       Seropositivity/*COMPLICATIONS/DIAGNOSIS  Joint Diseases/*COMPLICATIONS
       Male  Pain  Prospective Studies  Rwanda  JOURNAL ARTICLE

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