Document 0783
 DOCN  M9440783
 TI    HIV/AIDS and its implications for the control of animal tuberculosis
       [see comments]
 DT    9404
 AU    Daborn CJ; Grange JM; Centre for Tropical Medicine, Edinburgh
       University, Easter Bush,; Midlothian.
 SO    Br Vet J. 1993 Sep-Oct;149(5):405-17. Unique Identifier : AIDSLINE
       MED/94130079
 CM    Comment in: Br Vet J 1993 Sep-Oct;149(5):403-4
 AB    The HIV/AIDS pandemic is associated with a number of opportunist
       mycobacterial infections, principally tuberculosis and disease due to
       the avian tubercle bacillus, Mycobacterium avium. Tuberculosis occurring
       early in the course of HIV infection is usually caused by M.
       tuberculosis. However some cases are due to the bovine tubercle
       bacillus, M. bovis, which, in turn, is transmissible from man to
       animals, principally by the aerogenous route although the majority of
       cases in man are non-pulmonary. These two mycobacterial species may be
       differentiated by means of a set of simple tests. The quality and
       quantity of information on the world-wide distribution and prevalence of
       bovine and human tuberculosis due to M. bovis is not uniform. There is a
       notable paucity of information from the tropics but available reports
       suggest that there are significant levels of bovine tuberculosis. If
       correct, this information has serious public health implications in the
       light of the current HIV/AIDS epidemic. Urgent investigation is required
       so that appropriate control measures can be instituted where indicated
       and possible. The avian tubercle bacillus is a very common opportunistic
       pathogen in the late stage of AIDS but infection leading to disease is
       extremely rare in healthy, HIV-negative persons. Because of its
       widespread environmental distribution, infection by this pathogen cannot
       be prevented.
 DE    Adult  Aged  Animal  AIDS-Related Opportunistic Infections/*PREVENTION &
       CONTROL/  TRANSMISSION  Cattle  Child  Female  Human  Male  Middle Age
       Mycobacterium avium-intracellulare Infection/PREVENTION & CONTROL/
       TRANSMISSION  *Mycobacterium bovis/PATHOGENICITY  Mycobacterium
       tuberculosis/PATHOGENICITY  Tuberculosis/EPIDEMIOLOGY/*PREVENTION &
       CONTROL/TRANSMISSION  Tuberculosis, Bovine/*PREVENTION &
       CONTROL/TRANSMISSION  *Zoonoses  JOURNAL ARTICLE  REVIEW  REVIEW,
       TUTORIAL

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