Document 0912 DOCN M9440912 TI Identification of human T cell leukemia virus type IIb infection in the Wayu, an aboriginal population of Colombia. DT 9404 AU Ijichi S; Zaninovic V; Leon FE; Katahira Y; Sonoda S; Miura T; Hayami M; Hall WW; Division of Infectious Diseases, North Shore University Hospital,; Cornell University Medical College, Manhasset, New York 11030. SO Jpn J Cancer Res. 1993 Dec;84(12):1215-8. Unique Identifier : AIDSLINE MED/94124264 AB Human T cell leukemia virus type II (HTLV-II) is endemic in a number of native American populations and high rates of infection have also been demonstrated in intravenous drug abusers (IVDAs). Studies of virus isolates in the latter population have shown the existence of two closely related subtypes of the virus, HTLV-IIa and HTLV-IIb. To characterize the viruses present in native Americans, we analyzed by nucleotide sequence analysis the proviruses from the Wayu, an aboriginal population residing in Colombia, South America. The results showed HTLV-IIb infection in this population, and also demonstrated remarkable conservation of sequence when compared to the proviruses in IVDAs. DE *Aborigines Base Sequence Colombia Comparative Study Human HTLV-II/CLASSIFICATION/*GENETICS/ISOLATION & PURIF Leukemia, T-Cell, HTLV-II-Associated/COMPLICATIONS/*ETHNOLOGY/ *MICROBIOLOGY Molecular Sequence Data Substance Abuse/COMPLICATIONS United States JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).