Document 0943 DOCN M9440943 TI Magnetic resonance imaging in demyelinating, infectious, metabolic, and congenital diseases. DT 9404 AU Mechtler LL; Kinkel PR; Division of Neuroimaging Research, Millard Fillmore Hospitals,; Lucy Dent Imaging Center, Buffalo, NY 14209. SO Curr Opin Neurol. 1993 Dec;6(6):912-8. Unique Identifier : AIDSLINE MED/94122918 AB A mere 5 to 7 years ago, the majority of literature on demyelinating, infectious, metabolic, and congenital diseases of the brain focused on comparison between computed tomography and magnetic resonance imaging (MRI). MRI has become not only the foremost diagnostic tool in imaging of the central nervous system, but also a key research instrument. This is displayed by the recent increase in papers concerning magnetic resonance spectroscopy. It is perhaps no better illustrated than in the study of multiple sclerosis. A review of neuroimaging in infectious diseases places a heavy emphasis on AIDS-related infections. The ongoing development of new scan sequences, contrast agents, and fast scanning techniques are broadening our image of the brain and, indeed, our understanding of pathophysiologic mechanisms of disease states. Excellent examples of this are the metabolic and congenital diseases where, based on the knowledge of metabolic pathways and embryology, MRI has become the modality of choice. DE AIDS Dementia Complex/*DIAGNOSIS AIDS-Related Opportunistic Infections/*DIAGNOSIS Brain/ABNORMALITIES/PATHOLOGY Brain Diseases/*CONGENITAL/DIAGNOSIS Brain Diseases, Metabolic/*DIAGNOSIS Demyelinating Diseases/*DIAGNOSIS Human *Magnetic Resonance Imaging Multiple Sclerosis/DIAGNOSIS JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).