Document 0965
 DOCN  M9440965
 TI    HIV seropositivity among female prostitutes and nonprostitutes:
       obstetric and perinatal implications.
 DT    9404
 AU    Obi CL; Ogbonna BA; Igumbor EO; Ndip RN; Ajayi AO; Faculty of Science,
       Department of Biological Sciences; (Microbiology Unit), University of
       Lagos, Akoka, Nigeria.
 SO    Viral Immunol. 1993 Fall;6(3):171-4. Unique Identifier : AIDSLINE
       MED/94121745
 AB    Serum samples totaling 600 were obtained from female prostitutes (300)
       resident in different hotels in Lagos, Nigeria and nonprostitutes (300)
       attending different health centers for routine check-up in Lagos,
       Nigeria. Sera obtained were screened for the prevalence of HIV
       seropositivity among prostitutes in comparison with nonprostitutes by
       the enzyme linked immunosorbent assay (ELISA) using the Abbott test kits
       as recommended by the manufacturers. Positive sera were subjected to
       confirmatory testing using the Western Blot test-New Lav Blot I and II.
       Our results revealed that of the 300 prostitutes and nonprostitutes
       screened, 50 (16.67%) and 6 (2%) were HIV seropositive, respectively,
       and the difference was statistically significant (P < 0.01). For
       antibody to HIV-1, 44 (88%) and 5 (83%) of the positive cases recorded
       among prostitutes and nonprostitutes were seropositive. Four (8%) and
       one (16.67%) of the positive cases were HIV-2 seropositive for
       prostitutes and nonprostitutes, respectively. Only 2 (4%) of the
       positive samples from prostitutes showed reactivities with HIV-1 and
       HIV-2 (simultaneous infection or dual reactivity). Incidence of the dual
       reactivity was not recorded among the nonprostitutes screened. This
       study is expected to provide baseline data on HIV seropositivities among
       prostitutes and nonprostitutes in Nigeria. The biomedical application of
       this study is that it will also serve as strong evidence to indicate the
       high prevalence of HIV seropositivity among prostitutes in order to
       attract government intervention to step-up control measures.
 DE    Female  Human  HIV Antibodies/ANALYSIS  HIV
       Seropositivity/DIAGNOSIS/*EPIDEMIOLOGY  HIV Seroprevalence
       HIV-1/*IMMUNOLOGY  HIV-2/*IMMUNOLOGY  Incidence  Nigeria/EPIDEMIOLOGY
       Prostitution/*STATISTICS & NUMER DATA  JOURNAL ARTICLE

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