Document 0024 DOCN M9460024 TI [Visceral leishmaniasis and HIV infection: the diagnostic and therapeutic problems] DT 9404 AU Rocha PS; Rebocho L; Alvoeiro L; Lourenco G; Branco R; Victorino RM; de Moura MC; Servico de Medicina 2, Hospital Universitario de Santa Maria,; Lisboa. SO Acta Med Port. 1993 Nov;6(11):543-6. Unique Identifier : AIDSLINE MED/94189307 AB We present the case of an HIV-seropositive drug addict patient whose seropositivity was unknown until admission to hospital, where he presented with a clinical picture of fever splenomegaly and weight loss. A diagnosis of visceral leishmaniasis was established. We stress the diagnostic difficulties well expressed in the need to repeat the bone marrow aspirate to detect the presence of leishmanias. The lack of response to conventional antimonial therapy is discussed as well as the role of pentamidine as an alternative therapy. DE Adult Animal AIDS-Related Opportunistic Infections/*DIAGNOSIS/DRUG THERAPY Case Report Drug Therapy, Combination English Abstract Fever/DIAGNOSIS Hepatomegaly/DIAGNOSIS Heroin Dependence/COMPLICATIONS Human HIV Seropositivity/*DIAGNOSIS/DRUG THERAPY HIV-1/*IMMUNOLOGY Leishmania donovani/ISOLATION & PURIF Leishmaniasis, Visceral/*DIAGNOSIS/DRUG THERAPY Male Splenomegaly/DIAGNOSIS JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).