Document 0138
 DOCN  M9460138
 TI    Tc-99m DISIDA hepatobiliary scintigraphy in AIDS cholangitis.
 DT    9404
 AU    Brunetti JC; Van Heertum RL; Kempf JS; Yudd AP; Farman J; Department of
       Radiology, St. Vincent's Hospital & Medical Center; of New York.
 SO    Clin Nucl Med. 1994 Jan;19(1):36-42. Unique Identifier : AIDSLINE
       MED/94185366
 AB    Sixteen patients with documented AIDS cholangitis who underwent Tc-99m
       DISIDA hepatobiliary scintigraphy were retrospectively reviewed to
       assess the spectrum of changes observed in this disease. AIDS
       cholangitis was documented by either ERCP with aspiration/biopsy or the
       presence of typical sonographic/CT abnormalities with positive stool
       culture and a minimum of 6 months follow-up. Images were graded as
       regards parenchymal function (blood pool clearance, peak parenchymal
       activity, and degree of parenchymal retention), gallbladder
       visualization, presence of ductal dilatation, and time of intestinal
       activity. Three patterns were identified: 1) focal ductal dilatation
       with focal narrowing and focal or diffuse parenchymal retention; 2)
       ductal dilatation, without narrowing, and diffuse parenchymal retention;
       and 3) severe diffuse parenchymal retention with or without ductal
       abnormality. All 16 studies revealed abnormal parenchymal retention.
       Gallbladder nonvisualization was demonstrated in nine studies and
       delayed in two. The hepatobiliary scan is a very sensitive technique for
       evaluating AIDS cholangitis. Although a spectrum of findings may be
       observed, parenchymal retention with some degree of ductal abnormality
       is the most commonly observed pattern.
 DE    Adult  AIDS-Related Opportunistic Infections/EPIDEMIOLOGY/*RADIONUCLIDE
       IMAGING  Biliary Tract/*RADIONUCLIDE IMAGING
       Cholangitis/EPIDEMIOLOGY/ETIOLOGY/*RADIONUCLIDE IMAGING
       Cryptosporidiosis/*RADIONUCLIDE IMAGING  Cytomegalovirus
       Infections/*RADIONUCLIDE IMAGING  Female  Human  Imino Acids/*DIAGNOSTIC
       USE  Liver/*RADIONUCLIDE IMAGING  Male  Organotechnetium
       Compounds/*DIAGNOSTIC USE  Retrospective Studies  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
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