Document 0161
 DOCN  M9460161
 TI    Bacillary angiomatosis in a German patient with AIDS.
 DT    9404
 AU    Schneider T; Ullrich R; Schmitt-Graff A; Bergs C; Reiterer L; Dissmann
       T; Zeitz M; Riecken EO; Medizinische Klinik, Klinikum Steglitz, Freie
       Universitat; Berlin.
 SO    Clin Investig. 1993 Dec;72(1):50-4. Unique Identifier : AIDSLINE
       MED/94184118
 AB    A 52-year old male homosexual patient with acquired immunodeficiency
       syndrome (AIDS) presented in our clinic with multiple nodular papules
       (more than 100) spread over the whole body which had developed within 3
       months. Bacillary angiomatosis was suspected, which is a bacterial
       infectious disease recognized recently mainly in patients with AIDS.
       Histological and immunohistochemical examinations of extirpated skin
       lesions were in agreement with the diagnosis, and the detection of
       rod-shaped bacteria in the lesions by Warthin-Starry silver stain
       confirmed it. The patient was treated with 2 x 100 mg doxycycline per
       day. The fever disappeared, and the cutaneous lesions showed a slight
       tendency to improve. However, after 5 days of therapy the patient showed
       increasing weakness, with muscle and bone pain. The patient died 10 days
       after the doxycycline therapy had been started. The cutaneous lesions in
       bacillary angiomatosis may resemble Kaposi's sarcoma and may therefore
       be misdiagnosed. The disease may be fatal, but timely antibiotic
       treatment is usually effective; therefore, the diagnosis of bacillary
       angiomatosis is important. Although many cases have been reported from
       the United States, only one case is known from Europe. Our finding of
       bacillary angiomatosis in a German AIDS patient supports the concept of
       a worldwide distribution of this bacterial agent.
 DE    *Angiomatosis, Bacillary/DIAGNOSIS/DRUG THERAPY/PATHOLOGY  *AIDS-Related
       Opportunistic Infections/DIAGNOSIS/DRUG THERAPY/  PATHOLOGY  Case Report
       Doxycycline/THERAPEUTIC USE  Fatal Outcome  Human  Male  Middle Age
       JOURNAL ARTICLE

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