Document 0165 DOCN M9460165 TI A case control study on human immunodeficiency virus-1 (HIV-1) infection as a risk factor for tuberculosis and leprosy in western Kenya. DT 9404 AU Orege PA; Fine PE; Lucas SB; Obura M; Okelo C; Okuku P; Were M; Kenya Medical Research Institute, Alupe Leprosy and Skin Diseases; Research Centre, Busia. SO Tuber Lung Dis. 1993 Dec;74(6):377-81. Unique Identifier : AIDSLINE MED/94183979 AB A case control study was undertaken in Western Kenya from April 1989 to August 1990 to evaluate HIV-1 infection as a risk factor for tuberculosis and leprosy. The study involved 144 newly diagnosed sputum smear positive tuberculosis cases with 432 age, sex and neighbourhood-matched controls, and 132 diagnosed leprosy cases with 384 matched controls. Odds ratios obtained by conditional logistic regression (matched) analysis were 4.9 (95% CI 2.6, 6.8), and 1.8 (95% CI 0.9, 3.2), for the association between HIV-1 and tuberculosis and leprosy respectively. Approximately 31% of tuberculosis cases among males, and 11% of cases among females, were attributable to HIV infection. DE Adolescence Adult Age Distribution Aged AIDS-Related Opportunistic Infections/*COMPLICATIONS Case-Control Studies Child Child, Preschool Female Human HIV Seropositivity/COMPLICATIONS *HIV-1 Kenya Leprosy/*COMPLICATIONS Male Middle Age Risk Factors Sex Distribution Support, Non-U.S. Gov't Tuberculosis, Pulmonary/*COMPLICATIONS JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).