Document 0193 DOCN M9460193 TI HIV and pulmonary hypertension: a review. DT 9404 AU Mani S; Smith GJ; Department of Internal Medicine, Yale University School of; Medicine, New Haven, CT 06510. SO South Med J. 1994 Mar;87(3):357-62. Unique Identifier : AIDSLINE MED/94182161 AB We describe two unique cases of pulmonary hypertension in association with the human immunodeficiency virus (HIV) and review the 28 previously reported cases in the world literature. Our first patient has coexistent chronic active hepatitis, which has previously been associated with the development of plexogenic pulmonary hypertension; however, our second case clearly demonstrates a closer link between HIV infection and pulmonary hypertension. Unlike previously reported cases, our latter case was devoid of all other coexistent factors including intravenous drug abuse, hepatitis B antigenemia, coexisting immunologic lung parenchymal injury, and hepatitis. Additionally, this is the first case documenting the presence of asymptomatic type II cryoglobulins in an HIV-positive patient with plexogenic pulmonary hypertension. DE Adult Case Report Female Hepatitis B/COMPLICATIONS Hepatitis, Chronic Active/COMPLICATIONS Homosexuality Human Hypertension, Pulmonary/*COMPLICATIONS/PATHOLOGY HIV Infections/*COMPLICATIONS HIV Seropositivity/COMPLICATIONS Male Pulmonary Artery/ULTRASTRUCTURE JOURNAL ARTICLE REVIEW REVIEW, TUTORIAL SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).