Document 0201 DOCN M9460201 TI The distribution of T cell subsets of Kveim and sarcoid granulomata. An immunohistological investigation of blood, Kveim test sites and sarcoid tissue lesions from 16 patients. DT 9404 AU Tuzuner N; Ulku B; Uraz S; Gungen G; Demiric S; Celikoglu S; Department of Pathology, Cerrahpasa Medical School of Istanbul; University. SO Sarcoidosis. 1991 Mar;8(1):14-8. Unique Identifier : AIDSLINE MED/94181952 AB T lymphocyte subsets in a positive Kveim reaction and sarcoid tissue lesions as well as peripheral blood from 16 patients with sarcoidosis were evaluated with monoclonal antibodies. The data demonstrate a redistribution of T cells from the blood to the specifically involved tissues with granulomas, i.e., sarcoid tissue lesions and positive Kveim reaction. These cells express CD2+, CD4+ phenotype as demonstrated by high CD4/CD8 ratios at the sites of positive Kveim reaction and sarcoid tissue lesions with respect to blood. DE Adult CD4-CD8 Ratio Female Human Immunohistochemistry *Kveim Test Male Middle Age Sarcoidosis/*IMMUNOLOGY/PATHOLOGY Support, Non-U.S. Gov't *T-Lymphocyte Subsets JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).