Document 0244
 DOCN  M9460244
 TI    Population-based study of HIV-1 infection in 4,086 subjects in northwest
       Tanzania.
 DT    9404
 AU    Shao J; Brubaker G; Levin A; Kibauri A; Massesa E; Siso Z; Konings E;
       Clayton Y; Kumby D; Alexander S; et al; Muhimbili Medical Centre,
       Dar-es-Salaam, Tanzania.
 SO    J Acquir Immune Defic Syndr. 1994 Apr;7(4):397-402. Unique Identifier :
       AIDSLINE MED/94180315
 AB    A population-based HIV-1 seroprevalence survey of 4,086 individuals,
       aged 15-49 years, in the North Mara district of Tanzania from rural,
       periurban, and urban areas, including high-risk (prostitutes, and
       co-workers) individuals, was performed in 1989 and 1990. The overall
       seroprevalence was 7.3% (95% confidence interval, 6.5-8.1), with a
       gradient of seropositivity from high-risk 13.0% (9.1, 16.8), urban 8.8%
       (7.6, 10.0), periurban 6.5% (4.7, 8.4), to rural 2.6% (1.6, 3.7)
       subjects. Adjusted for population group, HIV-1 seroprevalence was
       significantly elevated for men over age 24 and for women 20-34 years
       old, while age-specific prevalence rates were similar for men and women
       in the rural area. Recent treponemal infection, measured by the rapid
       plasma reagin test, was not associated with HIV-1 seropositivity in men
       or women. These data suggest a growing HIV-1 epidemic paralleling rising
       rates in other rural areas of Africa distant from areas that have been
       previously recognized as having high prevalence.
 DE    Adolescence  Adult  Age Factors  Confidence Intervals  Female  Human
       HIV Antibodies/BLOOD  HIV Infections/COMPLICATIONS/*EPIDEMIOLOGY  *HIV
       Seroprevalence  HIV-1/*IMMUNOLOGY  Male  Middle Age  Odds Ratio
       Prevalence  Risk Factors  Rural Population  Sex Factors  Support, U.S.
       Gov't, P.H.S.  Syphilis/COMPLICATIONS/EPIDEMIOLOGY  Syphilis
       Serodiagnosis  Tanzania/EPIDEMIOLOGY  Urban Population  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).